Symptoms and Side Effects

Nausea and Vomiting

Person lying in bed, hands covering face, wearing a cozy sweater, relaxed and resting.

Managing Nausea and Vomiting

Nausea is the queasy, unsettled feeling in your stomach that often comes before vomiting. Vomiting is when you throw up. Many people experience nausea and vomiting as a side effect of cancer treatment; especially chemotherapy and radiation to areas like the brain, spine, or abdomen. These symptoms may also be caused by other medications, infections, anxiety, or constipation.

You may be more likely to experience nausea and vomiting during treatment if you:

  • Have had nausea with past treatments
  • Get motion sickness
  • Had morning sickness during pregnancy
  • Are younger than 50
  • Feel anxious before treatment
Person in a cozy sweater sitting in bed, holding a tissue and a water bottle, likely feeling unwell.

Types of Nausea and Vomiting

Different types of treatment-related nausea happen at different times. Understanding the timing can help you and your care team find the best ways to manage it:

  • Anticipatory Nausea: Happens before treatment starts—often due to anxiety or previous vomiting during treatment.
  • Acute Nausea: Starts within 1–2 hours after treatment, and may peak around 4–6 hours later.
  • Delayed Nausea: Begins more than 24 hours after treatment.

The likelihood and severity of nausea and vomiting depend on the specific chemotherapy drugs and your individual response. The good news? There are medications and strategies that help that we will cover below.

Anti-Nausea Medications

Your care team may prescribe anti-nausea and vomiting medicines based on your cancer treatment.

If you’re a candidate for any of these nausea-relief medications, follow these step:

  1. Take at the first sign of nausea, not after vomiting begins.
  2. Follow your care team’s instructions carefully, even on days when you feel okay.
  3. After each chemo cycle, share what worked (or didn’t work) with your team.

Keep in mind: Some nausea medicines can cause constipation. If constipation occurs, ask about stool softeners, such as Docusate 100 mg, 2–3 times/day or laxatives. Remember, always check before using over-the-counter drugs, including acetaminophen or cold medicines.

These descriptions do not include all important information about these medicines. See the medicine’s label for complete information. Ask your cancer care team if you have any questions.

Eating and Drinking to Help Nausea

Tip: Suck on ice chips, popsicles, or fruit ices between meals to stay hydrated

Before and After Treatment Tips

When to Call Your Care Team

Reach out right away if:

  • You can’t keep fluids down
  • You’re unable to swallow your medications
  • You vomit 6 or more times in 24 hours
  • You see blood or “coffee-ground”-like material in your vomit