Symptoms and Side Effects

Nail Changes

Person holding a wooden cleaning brush with bristles, preparing to clean a black surface with cotton swabs.

Caring for Nail Changes During Cancer Treatment

Some cancer treatments—like chemotherapy—can cause changes to your fingernails and toenails. These changes may affect how your nails look, grow, or feel, and can sometimes involve the skin around the nail. Most changes are temporary, but it’s important to take good care of your hands and feet and know when to call your care team.

Black hands with a tan background

What to Expect

If you’re receiving chemotherapy or other systemic treatments, you may notice:

  • Thicker or weaker nails
  • Soreness or pain around the nails
  • Redness or swelling near the nail
  • Changes in nail color
  • Ridges, pits, or other marks
  • Brittle or peeling nails
  • Lifting of the nail from the nail bed

Tips to Prevent Infection

  • Keep your nails clean and dry
  • Keep your nails short, but do not cut your cuticles
  • Check your hands and feet daily for changes
  • Tell your care team about any new or worsening nail symptoms
  • Avoid manicures and pedicures

How to Care for Your Nails

When to Call Your Care Team

Contact your care team right away if you experience:

  • A fever of 100.4° F (38° C) or higher
  • New or worsening redness, swelling, or pain around a nail
  • Pus or blisters near a nail